Isolation and Characterization of plasmid pKM 101 mutants Deficient in Their Ability to Enhance Mutagenesis

돌연변이율을 증가시키는 기능이 결여된 플라스미드 pKM101의 분리 및 그 특성에 관한 연구

  • 박찬규 (고려대 농대) ;
  • 하지홍 (고려대 농대) ;
  • 이세영 (고려대 농대)
  • Published : 1980.03.01


As preliminaries for the study of Plasmid pKM101 functions nad their interaction with the host DNA repair genes, seven mutants of pKM101, visualized on tetrazolium-galactose plates, deficient in their abitity to enhance mutagenesis were isolated and paritally characterizee. They all have altered functions not only for mutagenesis against MMS and 4-NQO but for the spontaneous reversion of host cell.