Studies on the Preparation of Radioactive iodine Labelled Concanavalin-A, Lectin Extracted from Korean Native Plant “Banha”, and Their Conjugation Products and the Hemagglutination Tests of These Labelled Compounds in Vitro.

  • Kim, You-Sun (Radio Organic Chemistry Lab., Korea Atonic Energy Research Institute, Seoul) ;
  • Park, Kyung-Bae (Radio Organic Chemistry Lab., Korea Atonic Energy Research Institute, Seoul)
  • Published : 1978.03.01

Abstract

Concanavalin-A, lectin extracted from Korean native plant “Banha”(Pine-llia Termata) and their conjugation products with tyrosine and 5-iodo-6-aminouracil were labelled by radioactive iodiae-125, and these labelled compounds were subjected to a hemagglutination test in vitro. The labelling procedures were presented with respect to labelling yield and the trends on the conjugation reaction of lectin with various amino acids were discussed. The preliminary results on the hemagglutination tests against cancer tissues were presented and the potential clinical applications of these labelled compounds were discussed.

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