Mutagenicity of Phenylenediamines and their Derivatives(I)

Phenylenediamine과 그 유도체들의 돌연변이 유발성 제1보

  • 변우현 (한국원자력연구소 분자생물학실) ;
  • 백상기 (한국원자력연구소 분자생물학실) ;
  • 이세영 (한국원자력연구소 분자생물학실)
  • Published : 1975.06.01


Mutagenic action of p-phenylenediamine(PA) and nitro-p-phenylenediamine(NPA) has been investigated using auxotroph mutants of S.typhimurium LT-2 strain. PA, the major component of hair day in South and East Asia and South America, was proved as potent frams-shift mutagen only after activation system. On the contrary, NAP was directly mutagenic in this system.