Monosodium Glutamate(MSG)가 초파리(Drosophila melanogaster)

• Published : 1973.06.01

Abstract

Monosodium glutamate(MSG) is a widely used food additive. Some reports descried its positive effect and the others, negative effect on mouse, monkey, human or drosophilid flies. Because of the conflicting reports the present investigation was undertaken to study the effects of MSG on the development of Drosophila melanogaster. The two strains of D. melanogaster, Oregon-R and Sinchon-I were used and MSG as well as cane sugar (as the second control) media were prepared by adding MSG or cane sugar at various concentrations to the standard food media for the present study. Ten flies (Male 5, Female 5) were placed in each vial and the numbers of $F_1$ flies emerged from it were counted. The results are presented below: 1. The numbers of $F_1$ flies decrease as the concentrations of MSG increase, implying that MSG has an inhibitory effect in the development of D. melanogaster. 2. The effects of cane sugar show an enhancing effect rather than an inhibitory one. 3. The numbers of $F_1$ fies produced in the Sinchon-I strain are greater than in the Oregon-R. This may be due to the difference in the length of inbred period. 4. The Muller-5 test shows a negative result, suggesting that MSG may be not mutagenic.