AGE AND GENDER DIFFERENCES IN ACUTE TOXICITY AND BLOOD-BRAIN BARRIER OPENING INDUCED BY SOMAN

  • Kim, Yun-Bae (College of Veterinary Medicine, Chungbuk National University)
  • Published : 2002.05.01

Abstract

The age- and gender-related differences in acute toxicity and opening of blood-brain barrier induced by an organophosphate soman were investigated in rats. To assess acute toxicity, young (7 weeks old) and old (12 weeks old) male and female rats were subcutaneously administered with various dose levels of soman.(omitted)