Endocrinology and Metabolism

The Korean Endocrine Society (대한내분비학회)
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A Case of Lymphocytic Hypophysitis in a Postmenopausal Woman

폐경후 여성에서 진단된 임파구성 뇌하수체염 1예

Baik, Sang-Hyun;Kim, Dong-Sun;Sung, Yoon-Kyoung;Kim, Jong-Pyo;Lee, Chang-Beom;Park, Yong-Soo;Choi, Woong-Hwan;Ahn, Yon-Hern;Kim, Tae-Wha;Ko, Yong;Park, Moon-Hyang
백상현;김동선;성윤경;김종표;이창범;박용수;최웅환;안유헌;김태화;고용;박문향

  • Published : 20020000
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Abstract

A 64-year-old Korean woman presented with a 3-week history of severe headache and ocular pain. Her brain MRI showed a cystic pituitary mass compressing the optic chiasm. A hormonal study revealed anterior pituitary insufficiency and a slightly increased prolactin level. We performed a transsphenoidal resection of the pituitary mass. A pathological examination revealed the presence of a heavy inflammatory infiltrate, composed of lymphocytes and plasma cells, and destruction of the adenohypophysial structures. Five months after surgery, her hormonal levels had nearly normalized, without hormone replacement therapy. A follow-up MRI showed no recurrence. We conclude that lymphocytic hypophysitis should be included in the differential diagnosis of pituitary mass at any age. We discuss the features that can help to make a preoperative differential diagnosis, and selection of the appropriate treatment.

저자들은 자가면역 질환의 증거가 없고 폐경기가 지난 여성에서 임파구성 뇌하수체염 1예를 수술적 치료 후에 확진하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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