A Case of Allergic Contact Dermatitis Due to Topical Minoxidil

Minoxidil 외용액에 의한 알레르기성 접촉피부염 1예

Kang, Kweon-Soo;Lee, Bo-Hyun;Han, Hee-Jin;Park, Chun-Wook;Lee, Cheol-Heon
강권수;이보현;한희진;박천욱;이철헌

  • Published : 20040400

Abstract

Minoxidil (2, 6-diamino-4-piperidinopyrimidine 1-oxide) is a systemic antihypertensive agent, the topical application of which has been shown to produce hair growth. Topical minoxidil solution (5% minoxidil, propylene glycol, alcohol, water) has generally been well-tolerated, but allergic contact dermatitis has been reported. When allergic contact dermatitis to minoxidil solution is suspected, evaluation of ingredients of minoxidil solution should be performed because allergic contact dermatitis due to propylene glycol in minoxidil solution has been frequently reported. A 34-year-old male presents with a diffuse erythematous patch on the scalp. He has applied minoxidil solution for 7 days due to androgenic alopecia. A Patch test with Korean standard series and the ingredients of used topical agents showed positive reactions to 1%, 2% and 5% minoxidil solution.

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References

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