Korean journal of dermatology (대한피부과학회지)

Korean Dermatological Association (대한피부과학회)
권호 표지

A Clinical Study of Androgenetic Alopecia

안드로겐성 탈모증의 임상적 고찰; 최근 10년간의 국내 보고들과 비교하여

Kang, Hyo-Joon;Kang, Seung-Hoon;Lee, Sang-Seok;Cho, Si-Hyung;Park, Sung-Wook
강효준;강승훈;이상석;조시형;박성욱

  • Published : 20041100
⟨ Previous Next ⟩

Abstract

Background: Androgenetic alopecia (AGA) is one of the most common type of alopecia among all men and women after puberty. The number of patients with AGA appears to be gradually increasing. Objectives: The purpose of this study was to investigate the clinical status such as age, family history, and type of patients with AGA and to review recent Korean literature. Methods: 1500 patients with AGA who had visited the Department of Dermatology, Busan Paik Hospital, Inje University School of Medicine during the last 7 years (from May 1997 through December 2003) were examined through the clinical records. Results: 1) There were 1162 male and 338 female patients being most prevalent in the third decade in both sexes. 2) In males AGA, Norwood-Hamilton's type II was the most common. 3) In females AGA, Ludwig's type I was the most common. 4) There was a family history of baldness in 62.9% of relatives in male patients and 48.8% in female patients. 5) The largest number of patients with AGA first visited our department when they had had 1-5 year's history of AGA in both sexes. 6) In the management of male AGA, oral finasteride only or with topical medications was the most common (72.4%) treatment modality. 7) In the management of female AGA, topical minoxidil solution only or with other topical medications was the most common (78.7%) treatment modality. Conclusions: The proportion of young patients with mild types appears to be high among AGA patients. It might be largely due to psychological stress in social situations.

Keywords

References

  1. Chua-Ty G, Goh CL, Koh SL. Pattern of skin diseases at the National Skin Centre (Singapore) from 1989-1990 Int I Dermatol 1992;31:555-559
  2. 강진수，박기범. 서부 경남지역 피부질환의 통계적 고찰(1987-1990). 대피지 1991;29:399-406
  3. Adachi K, Kano M. Adenyl cyclase in human hair follicles: Its inhibition by dihydrotestosterone. Biochem Biophys Res Commun 1970;41:884-890
  4. Elis A. Oslen. Androgenic alopecia. In: Elis A. Oslen, editors. Disorders of hair growth diagnosis and treatment. 1st ed. New York: McGraw-Hill, 1994;257-284
  5. Norwood OT. Male pattern baldness: classification and incidence. South Med J 1975;68:1359-1365
  6. Ludwig E. Classification of the types of androgenetic alopecia (common baldness) occurring in the female sex. Br I Dermatol 1977;97:247-254
  7. Hamilton JB. Patterned loss of hair in man: Types and incidence. Ann N Y Acad Sci 1951;53:708-728
  8. Montagna W. Baldness: a disease? I Am Med Womens Assoc 1973;28:447-450
  9. Hamilton JB. Male hormone stimulation is prerequisite and an incitant in common baldness. Am I Anat 1942;71:451-80
  10. Ludwig E. The role of sexual hormone in pattern alopecia. In: Biopathology of pattern alopecia. New York: Darger, 1968:50-60
  11. Futterweit W, Dunaif A, Yeh HC, et al. The prevalence of hyperandrogenism in 109 consecutive female patients with diffuse alopecia. I Am Acad Dermatol 1988;19:831836
  12. Georgala S, Gourgiotou K, Kassouli S, et al. Hormonal status in postmenopausal androgenetic alopecia. Int J Dermatol 1992;31:858-859
  13. Fauze M, Drapier-Fraure E. Hormonal assessment in a woman with acne and alopecia. Revue Francaise de Gynecologie et de Obstetrique(Abstract) 1992;87:331-334
  14. Pitts RL. Serum elevation of dehydroepiandrosterone sulfate associated with male pattern baldness in young men. I Am Acad Dermatol 1987;16:571-573
  15. 한은실，김명남，홍창권，노병인. 안드로겐성 탈모증의 임상적 고찰 대피지 1995;33:44-45
  16. 임현상，이창균，노병인. 안드로겐성 탈모증의 임상적 고찰. 대피연지 1997;4:27-34
  17. JH Shim, SW Ro, BI Ro. A clinical study of androgenetic alopecia(III). Ann Dermatol 2002;14:11-17
  18. 정유선，탁우정，노병인. 안드로겐성 탈모증의 임상적 고찰(제 4보) . 대피지 2002;40:785-790
  19. 유재학，은희철，김계정，문상은. 한국인에 있어 유전성 안드로겐 탈모증의 유병율과 엄상 유형. 대피지 1995;33:67-75
  20. Paik JH, Yoon JB, Sim WY, Kim BS, Kim NI. The prevalence and types of androgenetic alopecia in Korean men and women. Br I Dermatol 2001;145:95-99
  21. 이준상，임철완. 탈모증 환자 1505명의 임상적 연구. 대피지 2000;38: 1348-1357
  22. 김휘준，심우영，송지영. 남성형 탈모증 환자의 질병행동 특성과 삶의 질에 관한 연구. 대피지 2001;39:1094-1099
  23. Cash TF. The psychological effects of androenetic alopecia in men. J Am Acad Dermatol 1992;26:926-931
  24. Cash TF, Price VH, Savin RC. Psychological effects of androgenetic alopecia on women: comparisons with balding men and with female controls. J Am Acad Dermatol 1993;29:568-575
  25. Gupta MA, Gupta AK. Age and gender differences in the impact of psoriasis on quality of life. Int J Dermatol 1995;34:700-703
  26. Fortune DG, Richard HL, Main CJ, Griffiths CE. What patients with psoriasis is believe about their condition. J Am Acad Dermatol 1998;39:196-201
  27. Choi J, Koo JH. Quality of life issues in psoriasis. J Am Acad Dermatol 2003;49:S57-61
  28. 이정화，김유찬，박향준，신용우，이경규. 원형탈모증에서의 불안, 우울 및 정신과적 증상에 관한 연구. 대피지 1997;35:837-846
  29. Bouhanna PAndrogenetic alopecia: combining medical and surgical treatments Dermatol Surg 2003;29:1130-1134
  30. TostiA, Camacho-Martinez F, Dawber R Management of androgenetic alopecia J Eur Acad Dermatol Venereo 1999;12:2051
  31. Bazzano G, Terexakis N, Galen W. Topical tretinoin for hair growth promotion. J Am Acad Dermatol 1986;15:880-883,890-893
  32. Rushton DH, Ramsay ID. The importance of adequate serum ferritin levels during oral cyproterone acetate and ethinyl oestradiol treatment of diffuse androgen-dependent alopecia in woman. Clin endocrinol 1992;36:421-427